Yaqing Zhang, David Kuster, Tobias Schmidt, Daniel Kirrmaier, Gabriele Nübel, David Ibberson, Vladimir Benes, Hans Hombauer, Michael Knop, Andres Jäschke

Chemical Science 12 (2020)

NEW RNA MODIFICATIONS IN BIOLOGY

Single-step discovery of high-affinity RNA ligands by UltraSelex

Y Zhang, Y Jiang, D Kuster, Q Ye, W Huang, S Fürbacher, J Zhang, P Doll, W Lin, S Dong, H Wang, Z Tang, D Ibberson, K Wild, I Sinning, AA Hyman, A Jäschke

Nature Chemical Biology, 1-9 (2025)

Flavin Adenine Dinucleotide (FAD) as a Non-Canonical RNA Cap: Mechanisms, Functions, and Emerging Insights

P Gonzalez-Jabalera, A Jäschke

Archives of Biochemistry and Biophysics, 110326

Thiophosphate Analogs of Coenzyme A and Its Precursors—Synthesis, Stability, and Biomimetic Potential

C Löcherer, E Tosun, H Backes, A Jäschke

Biomolecules 12

Staphylococcus aureus Small RNAs Possess Dephospho-CoA 5′-Caps, but No CoAlation Marks

C Löcherer, N Bühler, P Lafrenz, A Jäschke

Non-coding RNA 8

Synthesis of 5′-Thiamine-Capped RNA

M Möhler, K Höfer, A Jäschke

Molecules 25

Analysis of 5′-NAD capping of mRNAs in dormant spores of Bacillus subtilis

DL Craft, G Korza, Y Zhang, J Frindert, A Jäschke, MJ Caimano, P Setlow

FEMS Microbiology Letters 367

A novel NAD-RNA decapping pathway discovered by synthetic light-up NAD-RNAs

F Abele, K Höfer, P Bernhard, J Grawenhoff, M Seidel, A Krause, S Kopf, A Jäschke

Biomolecules 10

The 5′ NAD cap of RNAIII modulates toxin production in Staphylococcus aureus isolates

HG Morales-Filloy, Y Zhang, G Nübel, SE George, N Korn, C Wolz, A Jäschke

Journal of Bacteriology 202

Extensive 5'-Surveillance Guards Against Non-Canonical NAD-Caps of Nuclear mRNAs in Yeast

Y Zhang, D Kuster, T Schmidt, D Kirrmaier, G Nübel, D Ibberson, V Benes, A Jäschke

Nature Communications 11

PHOTOSWITCHABLE BIOMOLECULES

A DNA‐based two‐component excitonic switch utilizing high‐performance diarylethenes

SM Büllmann, T Kolmar, NF Zorn, J Zaumseil, A Jäschke

Angewandte Chemie 61

Development of Red‐Shifted and Fluorogenic Nucleoside and Oligonucleotide Diarylethene Photoswitches

T Kolmar, A Becker, RA Pfretzschner, A Lelke, A Jäschke

Chemistry–A European Journal 27

Development of High‐Performance Pyrimidine Nucleoside and Oligonucleotide Diarylethene Photoswitches

T Kolmar, SM Büllmann, C Sarter, K Höfer, A Jäschke

Angewandte Chemie 133

“Click-switch”–one-step conversion of organic azides into photochromic diarylethenes for the generation of light-controlled systems

S Becht, R Sen, SM Büllmann, A Dreuw, A Jäschke

Chemical Science 12

Optochemical control of transcription by the use of 7-deaza-adenosine-based diarylethenes

SM Büllmann, T Kolmar, P Slawetzky, S Wald, A Jäschke

Chemical Communications 57

Norbornadiene-bridged diarylethenes and their conversion into turn-off fluorescent photoswitches

SM Büllmann, A Jäschke

Chemical Communications 56

RNA IMAGING

Super-resolved protein imaging using bifuntional light-up aptamers

F Grün, N van den Bergh, M Klevanski, M S.Verma, B Bühler, G. Ulrich Nienhaus, T Kuhner, A Jäschke, M Sunbul

Angewandte Chemie Int Ed Engl 2024 Aug

Programmable, Structure-Switching RhoBAST for Hybridization-Mediated mRNA Imaging in Living Cells

B Bühler, J Schokolowski, A Jäschke, M Sunbul

ACS Chemical Biology

Fast-exchanging spirocyclic rhodamine probes for aptamer-based super-resolution RNA imaging

D Englert, EM Burger, F Grün, MS Verma, J Lackner, M Lampe, B Bühler, J Schokolowski, G. U. Nienhaus A. Jäschke & M. Sunbul

Nature Communications 14 (1)

Avidity-based bright and photostable light-up aptamers for single-molecule mRNA imaging

B Bühler, J Schokolowski, A Benderoth, D Englert, F Grün, A Jäschke, M Sunbul

Nature Chemical Biology, 1-10

A Color‐Shifting Near‐Infrared Fluorescent Aptamer–Fluorophore Module for Live‐Cell RNA Imaging

J Zhang, L Wang, A Jäschke, M Sunbul

Angewandte Chemie 133

Super-resolution RNA imaging using a rhodamine-binding aptamer with fast exchange kinetics

M Sunbul, J Lackner, A Martin, D Englert, B Hacene, F Grün, K Nienhaus, G. U. Nienhaus, A Jäschke

Nature Biotechnology 39

Aptamer-based proximity labeling guides covalent RNA modification

D Englert, R Matveeva, M Sunbul, R Wombacher, A Jäschke

Chemical Communications 57

SiRA: a silicon rhodamine-binding aptamer for live-cell super-resolution RNA imaging

R Wirth, P Gao, GU Nienhaus, M Sunbul, A Jäschke

Journal of the American Chemical Society 141

ORIGIN OF LIFE

Triplet-encoded prebiotic RNA aminoacylation

M Su, C Schmitt, Z Liu, SJ Roberts, KC Liu, K Röder, A Jäschke,DJ Wales, JD Sutherland

Journal of the American Chemical Society, 145(29) (2023).

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